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2003-10

2008/04/08(Tue) 13:04

Effect of High Magnetic Field for the Ice/water Interfacial Adsorption of Antifreeze Glycoprotein Molecules
不凍糖タンパク質の氷/水界面吸着状態に対する強磁場の効果

Antifreeze Glycoprotein (AFGP), which is known as a special protein to inhibit the freezing of living organisms under subzero environment, adsorbs at the interface between ice and water and affects the growth rates and growth morphologies of ice crystals. We detected the growth rates of ice crystals are also strongly changed by the effect of high magnetic field. This result indicates that the orientations of AFGP molecules adsorbed at the ice/water interface can be modified by the effect of magnetic field and the high magnetic field is useful for the investigations of the adsorption state of macromolecules.

Inst. Low Temp. Sci., Hokkaido University: Y. Furukawa, K. Nomura, C. Katagiri
Inst. Protein Res., Osaka University: Y. Matsuura
IMR, Tohoku University: I. Mogi
Reference: Y. Furukawa, Y. Matsura, K. Nomura, C. Katagiri, I. Mogi, "Effect of high magnetic field for the ice/water interfacial adsorption of antifreeze glycoprotein molecules", to be published.

生体の凍結を抑制するタンパク質として知られる不凍糖タンパク質(AFGP)は,氷と水の界面に吸着して氷の結晶成長速度や結晶の成長形に大きな影響を与える.強磁場中でAFGP水溶液からの氷結晶の自由成長実験を行うと,氷結晶成長速度が大幅に変化することが見出された.これは,界面に吸着したタンパク質の配向が磁場の効果で変化したことを示唆し,AFGP分子の界面吸着状態の解明に強磁場実験が有効であることを示した.

北海道大学 低温科学研究所:古川義純,野村耕介,片桐千仭
大阪大学 蛋白質研究所:松浦良樹
東北大学 金属材料研究所:茂木 巌