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2008/04/08(Tue) 14:32

Biological Responses to High Magnetic Fields in Caenorhabditis Elegans: Monitoring Chromosomal DNA Breaks and Apoptosis

In this study, the influences of the static high magnetic fields (MFs) on DNA damage such as DNA double-strand (ds) breaks, apoptosis, and alterations of entire gene expression were investigated using a model metazoan Caenorhabditis elegans. Under the 2T to 5T MFs, no increments of ds breaks and apoptosis were observed. In addition, certain genes including hsp-16, which respond to several environmental stresses, were up-regulated but not DNA damage-induced genes. These results indicate that static high MFs did not introduce any DNA damage, although extremely-low-frequency MFs is known as possible health hazards including the ds breaks.

Grad. School of Life Sci., Tohoku University: A. Higashitani, Y. Konishi, Y. Suzuki
NICHe, Tohoku University: R. Saito, E. Ichiishi
IMR, Tohoku University: K. Takahashi, S. Awaji, K. Watanabe


東北大学金属材料研究所:高橋弘紀,淡路 智,渡辺和雄